Chemistry in the News

What is folic acid, and why is it important during pregnancy?

Infographic titled 'Why is folic acid important during pregnancy?'. Folic acid is a human-made form of folate, vitamin B9. We have to get it from our diet. It's converted into folate in the body. Folate is found naturally in a number of foods, particularly leafy vegetables, seeds, and nuts. It can also be added to some foods including flour, a process known as fortification. Low levels of folate have been linked to neural tube defects (NTDs). These happen when the neural tube, which forms the brain and spinal cord, doesn't develop or close properly, leading to conditions like spina bifida. Taking folic acid before and during early pregnancy reduces the risk of NTDs by about 70%. The mechanism by which folate reduces NTDs isn't known, but folate is important for building nucleic acids, the building blocks of DNA. Large quantities of nucleic acids are required by the developing neural tube for DNA replication, and folic acid deficiency may impact this.
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This week, the UK has confirmed it plans to fortify non-wholemeal flour with folic acid. It’s not the first country to do so: the United States has been fortifying flour with folic acid since 1998. Most countries in South America and a number in Asia also have mandatory fortification programs. This graphic looks at the reasons for fortification with folic acid – and making it also got me wondering why the practice isn’t more widespread in Europe.

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An infographic in the Chem vs COVID timeline series. On 6 July 2020, scientists called for greater recognition of the airborne transmission of SARS-CoV-2. People infected with COVID-19 expel droplets when they talk, cough, sneeze, or even breathe. Large droplets travel short distances and can contaminate surfaces, though research has suggested this is a less significant mode of transmission than initially thought. Very small droplets dry and form aerosols (particles suspended in air) which can travel greater distances and spread the virus through the air. Chemists have produced antiviral coatings, containing metals or polymers, to reduce surface transmission. Ventilation and air purification technologies such as air filters, UVC light and photocatalytic devices can destroy the virus in the air in buildings. Overall, understanding of transmission and preventative technologies have helped limit infections, make activities safer, and improved technology to combat viruses in the future.

#ChemVsCOVID: How chemistry is helping with understanding and combatting virus transmission

An infographic in the Chem vs COVID timeline series. On 6 July 2020, scientists called for greater recognition of the airborne transmission of SARS-CoV-2. People infected with COVID-19 expel droplets when they talk, cough, sneeze, or even breathe. Large droplets travel short distances and can contaminate surfaces, though research has suggested this is a less significant mode of transmission than initially thought. Very small droplets dry and form aerosols (particles suspended in air) which can travel greater distances and spread the virus through the air. Chemists have produced antiviral coatings, containing metals or polymers, to reduce surface transmission. Ventilation and air purification technologies such as air filters, UVC light and photocatalytic devices can destroy the virus in the air in buildings. Overall, understanding of transmission and preventative technologies have helped limit infections, make activities safer, and improved technology to combat viruses in the future.
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How does COVID spread? Of all the questions about the pandemic, this seems like it would be a fairly simple one to answer. But, even several months into the pandemic, the guidance from public health organisations did not recognise the potential for COVID to be transmitted through the air. The latest edition of the Chem vs. COVID series with the Royal Society of Chemistry highlights the point at which scientists called for this mode of transmission to be more widely recognised.

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How do air purification technologies work? – in C&EN

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With the ongoing COVID-19 pandemic, air purification technologies have been receiving renewed attention as workplaces look for solutions that will lower their workers’ risk of exposure. In the latest edition of Periodic Graphics in Chemical and Engineering News, we take a look at the different types of air purification and how each of them works. View the full graphic on the C&EN site.

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#ChemVsCOVID: How were the first treatments for COVID identified?

An infographic titled "Chem vs COVI timeline: 16th June 2020, RECOVERY trial shows dexamethasone as first effective COVID-19 treatment". The structure of dexamethasone is shown at the centre. The left-hand side of the graphic explains how the RECOVERY trial aimed to identify existing treatments that work against COVID-19. 12 treatments were trialled at 181 sites with over 40,000 participants. As of June 2021, 3 treatments have been shown to be effective, and 4 treatments have been shown to be ineffective. The right-hand side of the infographic explains that dexamethasone has antiinflammatory and immunosuppressant effects which may explain the positive results. It's estimated that dexamethasone has saved 22,000 lives in the UK and 1,000,000 lives worldwide. The RECOVERY trial has also shown which treatments are ineffective, including hydroxychloroquine, and set a precedent for how large-scale trials can be carried out during an emergency situation.
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On this day (16 June) a year ago, the first effective treatment for COVID-19 was announced. The corticosteroid drug dexamethasone, already used to treat several inflammatory and autoimmune conditions, was found to be effective for patients in a serious condition in hospital with COVID. This discovery was the product of the RECOVERY trial, a programme started in March 2020 to find COVID treatments.

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#ChemVsCOVID: How did past research help COVID-19 vaccine efforts?

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On this day in 2020, the Moderna COVID-19 vaccine entered phase 1 trials, making it the first COVID vaccine to do so. This came less than a week after the World Health Organisation declared COVID-19 a global pandemic. How was it possible for this to happen so quickly? The third part of the #ChemVsCOVID series, produced with the Royal Society of Chemistry, gives a brief overview of the prior work and what the phase 1 trials looked at.

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