Categories
Chemunicate Medicinal Chemistry

Finding More Stable Forms of Drugs Using Full Interaction Maps

When pharmaceutical companies manufacture a drug, finding the drug’s most stable form is important. Not only do drugs become less effective as they degrade, limiting their useful shelf life, but if a more stable version of a drug is discovered after it has reached the market, products may end up being withdrawn, costing money. As a […]

Categories
Chemunicate Medicinal Chemistry

Protein Fragment Hotspots: Helping the Design of Better Medicines

This latest Chemunicate graphic (the Compound Interest side project that works with chemistry researchers and institutions to highlight their research in graphical form) was made for the Cambridge Crystallographic Data Centre, and takes a look at a particular computational method that can be used to assist in the discovery of drug molecules.

Categories
Biochemistry C&EN Medicinal Chemistry

Tackling Stress and Anxiety with Chemistry

Christmas is meant to be a relaxing time spent with family, but gift-shopping and family dinners can sometimes pile on the stress over the holiday period. For others, anxiety is a year-round battle. In this month’s edition of Periodic Graphics in C&EN, we take a basic look at the chemical causes of stress, and the medications […]

Categories
C&EN Medicinal Chemistry

The Chemistry of Cold Medicines – in C&EN

Having been struck down by a cold over the past few days, I was reminded of this old edition of Periodic Graphics that appeared in C&EN last year, which looks at the chemistry of cold medicines. I’m definitely grateful for a number of these right now! Click through to the C&EN site to view the full […]

Categories
Medicinal Chemistry Sport Chemistry

A Brief Guide to Doping in Sports

The Rio Olympics are underway, and after a build-up that’s already been marred by the Russian doping scandal, officials will be on the look-out for athletes trying to gain an edge by using performance-enhancing drugs. What types of drugs will they be looking for, and why might athletes be tempted to use them in the […]

Categories
C&EN Medicinal Chemistry Sport Chemistry

The Chemistry Behind the Russian Doping Scandal – in C&EN

The run-up to the Rio Olympics has been overshadowed by a number of issues, not least of which is the doping scandal surrounding Russian competitors. This month’s Periodic Graphics in C&EN looks at the alleged chemical cocktail that was used to dope Russian athletes at the 2012 London Games and in the 2014 Sochi Winter […]