Categories
Biochemistry Medicinal Chemistry

What links snowdrops, Alzheimer’s disease, and chemical warfare?

Snowdrops and chemical warfare aren’t two things you’d expect to mention in the same sentence. However, there’s a surprising link between the two thanks to a compound found in these winter flowers. This graphic looks at this compound and how it helps treat both Alzheimer’s disease and nerve agent poisoning.

Categories
Chemistry History Medicinal Chemistry

Today in Chemistry History: Gertrude B Elion and drug discovery firsts

Today, 23 January, marks the birthday of Gertrude B Elion, a chemist who jointly won the Nobel Prize in Physiology or Medicine for her work on drug treatments and the discovery of several drugs used to treat a variety of diseases. This graphic takes a look at some of the key medicines she discovered.

Categories
C&EN

The Chemistry behind the Opioid Epidemic – in C&EN

In the U.S in 2015, opioid overdoses were responsible for over 33,000 deaths. In this month’s edition of Periodic Graphics in Chemical & Engineering News, we take a look at the chemicals behind this surge in overdose deaths, and the treatments currently available to reverse opioid overdose and addiction. View the full graphic on the C&EN […]

Categories
Chemunicate Medicinal Chemistry

Combating Chemoresistance: Blocking DNA Repair to Fight Cancer

In 2012, the most recent year for which the information is available, there were 8.2 million cancer-related deaths worldwide. Chemotherapy is a common treatment resort, but it’s by no means a magic bullet, and this is often due to chemoresistance. This latest Chemunicate graphic, made on behalf of Thomas Fleming at the University of Oxford, looks at […]

Categories
Chemunicate Medicinal Chemistry

Finding More Stable Forms of Drugs Using Full Interaction Maps

When pharmaceutical companies manufacture a drug, finding the drug’s most stable form is important. Not only do drugs become less effective as they degrade, limiting their useful shelf life, but if a more stable version of a drug is discovered after it has reached the market, products may end up being withdrawn, costing money. As a […]

Categories
Chemunicate Medicinal Chemistry

Protein Fragment Hotspots: Helping the Design of Better Medicines

This latest Chemunicate graphic (the Compound Interest side project that works with chemistry researchers and institutions to highlight their research in graphical form) was made for the Cambridge Crystallographic Data Centre, and takes a look at a particular computational method that can be used to assist in the discovery of drug molecules.