Categories
Medicinal Chemistry

Understanding the Drug Discovery Process

Drug testing was in the news on Friday – though this time it wasn’t the usual sports doping headlines, but instead news of the clinical trial of a drug gone tragically wrong in France. Of the 90 people given the drug in a phase 1 clinical trial, one has been left with permanent brain damage, […]

Categories
Food Chemistry

Why does Grapefruit Interact with Drugs? – The Chemistry of a Grapefruit

You may have heard of ‘the grapefruit juice effect’ – a range of medications recommend avoiding grapefruits or grapefruit juice whilst you are taking them, due the unfavourable interactions with the medication and the unwanted side effects this can cause. So, what chemical compounds cause these interactions?