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C&EN Medicinal Chemistry

A brief history of anaesthetics and how they work – in C&EN

Surgery has become a lot more comfortable since the first demonstrations of ether anaesthesia in the 1840s. In October’s edition of Periodic Graphics in Chemical & Engineering News, we looked at the different types of anaesthesia, the compounds involved, and what we know about how they work. Click through to the C&EN site to view […]

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ChemVsCOVID Medicinal Chemistry

#ChemVsCOVID: How nucleoside analogue antivirals combat COVID

One year ago, in October 2020, the US FDA approved remdesivir: the first antiviral drug approved for COVID-19. While it’s not as effective as was first thought, similar drugs look like they could be more successful. The latest graphic in the #ChemVsCOVID series with the Royal Society of Chemistry examines how they work.

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ChemVsCOVID Medicinal Chemistry

#ChemVsCOVID: How were the first treatments for COVID identified?

On this day (16 June) a year ago, the first effective treatment for COVID-19 was announced. The corticosteroid drug dexamethasone, already used to treat several inflammatory and autoimmune conditions, was found to be effective for patients in a serious condition in hospital with COVID. This discovery was the product of the RECOVERY trial, a programme […]

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Chemistry in the News Coronavirus Medicinal Chemistry

What are the COVID-19 RNA vaccines and how do they work?

By now, we’re all familiar with the image of coronavirus. The spikey blob peppers news websites, looms behind reporters during bulletins and frequently punctuates your Twitter doom-scrolling. More recently, the news accompanying this image has taken a positive turn, with promising results from the COVID-19 vaccine trials. It’s the iconic spikes of the coronavirus spikey […]

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C&EN Coronavirus Medicinal Chemistry

A guide to COVID-19 testing – in C&EN

We’re several months into the COVID-19 pandemic, and testing is vital to preventing the spread of the novel coronavirus. The latest edition of Periodic Graphics in Chemical and Engineering News looks at how current diagnostics work and what they tell us. Click to view the full graphic on the C&EN site.

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Chemistry in the News Coronavirus Medicinal Chemistry

Antibody tests, part 2: How do antibody tests work?

Last week, we looked at what coronavirus antibody tests can and can’t tell us. In part 2 of this series of graphics on antibody testing, we look at how the tests work to arrive at their results. As we’ll see, there’s not only one type of antibody test and they can vary in accuracy and […]